Around 1 in 8 American adults have taken a GLP-1 drug containing semaglutide, more than a third of them for weight loss. With such high demand, med spas are looking to semaglutide injections as a valuable offer to package with aesthetic weight loss treatments.
What Is Semaglutide?
Semaglutide is a drug that regulates appetite and blood sugar levels. It was first approved by the FDA in 2017 to treat Type 2 diabetes; a second formulation specifically for weight loss was FDA-approved in 2021.
Who Qualifies for Semaglutide Injections?
Semaglutide is only available by prescription, so adding it to a patient’s weight-loss program requires the involvement of a medical clinician.
Each state has its own requirements for which clinicians can prescribe and administer semaglutide injections, and some have additional requirements.
For example, Connecticut requires patients on semaglutide to participate in a counseling and wellness program in conjunction with their treatment.
Jump to your state's requirements
Semaglutide is approved for weight management in adults with a BMI over 30. It can be prescribed to adults with a BMI over 27 if the patient also has a weight-related medical condition.
Nextech’s med spa-specific platform stays up to date on changing regulations, making it easier for your business to stay in compliance. Request a demo.
Offering Semaglutide at Your Med Spa
If a patient is interested in semaglutide for weight loss, med spas can be the ideal prescriber, since injections can be packaged with aesthetic treatments not available at a primary care doctor’s office.
You can increase the profitability of your med spa’s semaglutide offering by packaging injections with skin tightening, muscle sculpting, and body sculpting treatments.
Semaglutide and Skin Tightening
A well-known side effect of rapid weight loss is loose, sagging skin. This is so common among semaglutide patients, it’s been given an unflattering nickname.
Ease patients’ concerns about sagging and wrinkles by bundling semaglutide injections with radiofrequency skin tightening to restore firmness.
Semaglutide and Muscle Sculpting
Along with losing fat, some semaglutide patients lose muscle tone as their weight rapidly drops.
Med spas offering a combination of radiofrequency and high-intensity focused electromagnetic (HIFEM) energy treatments can package them with semaglutide injections to tone muscles and increase metabolism, helping patients keep the weight off.
Semaglutide and Non-Surgical Body Sculpting
Like any weight-loss program, semaglutide injections do not necessarily cause people to lose weight evenly from their entire body. Patients may still struggle with hard-to-lose fat in areas like the lower abdomen and hips.
Bundling semaglutide with sculpting treatments like cryolipolysis assures patients they can actually achieve the body they dreamed of.
Nextech’s Med Spa for Wellness and Weight Loss technology increases revenue by an average of 70% per patient encounter. Request a demo.
Semaglutide Laws Changed in 2025
From the time semaglutide was approved for weight loss in 2021 through the end of 2024, a multitude of vendors popped up offering versions of the drug, not all of them safe and effective.
In 2022, a semaglutide shortage led the FDA to allow sales of compounded GLP-1s. The market was flooded with compounds using various types and grades of semaglutide.
In February 2025, the FDA declared the shortage was over. Since April 2025, it has been illegal to prescribe and compound GLP-1 medications that are essentially a copy of FDA-approved drugs.
Potential exceptions exist when the prescriber can show a patient has a medical need for a formulation significantly different from the commercial product, for example, an allergy to an inactive ingredient in the approved drug.
Penalties for selling and administering drugs not approved by the FDA can include fines, loss of license, and criminal charges, as well as opening a practice to civil liability claims from patients and their families.
Who Can Prescribe and Administer Semaglutide Injections?
In many states, semaglutide drugs can only be prescribed by a physician or nurse practitioner, though some states also grant prescriptive authority to physician assistants and advanced practice registered nurses.
Can Semaglutide Be Prescribed Online?
Legally, semaglutide can be prescribed online as long as the provider has prescriptive authority. Some states, like Arkansas, require the initial patient exam be done in person, though they allow telemedicine for follow-up visits.
Telemedicine laws in most states require online visits meet the same standard of care as in-person visits. So if a test or measurement would be considered during an in-person exam, it should be ordered for the telemedicine exam, too.
Related: Med Spa Laws by State
Semaglutide Laws By State
If your clinic or med spa is considering offering semaglutide for weight loss, be sure to check with your state medical board first. This list of regulations is not exhaustive, and state laws often change. (Note: This blog post is for general informational purposes only and is not legal advice.)
Alabama | Alaska | Arizona | Arkansas | California | Colorado | Connecticut | Delaware | Florida | Georgia | Hawaii | Idaho | Illinois | Indiana | Iowa | Kansas | Kentucky | Louisiana | Maine | Maryland | Massachusetts | Michigan | Minnesota | Mississippi | Missouri | Montana | Nebraska | Nevada | New Hampshire | New Jersey | New Mexico | New York | North Carolina | North Dakota | Ohio | Oklahoma | Oregon | Pennsylvania | Rhode Island | South Carolina | South Dakota | Tennessee | Texas | Utah | Vermont | Viriginia | Washington | West Virginia | Wisconsin | Wyoming
Alabama
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Alaska
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Arizona
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Arkansas
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California
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Colorado
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Connecticut
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Delaware
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Florida
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Georgia
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Hawaii
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Idaho
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Illinois
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Indiana
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Iowa
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Kansas
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Kentucky
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Louisiana
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Maine
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Maryland
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Massachusetts
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Michigan
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Minnesota
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Mississippi
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Missouri
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Montana
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Nebraska
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Nevada
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New Hampshire
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New Jersey
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New Mexico
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New York
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North Carolina
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North Dakota
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Ohio
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Oklahoma
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Oregon
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Pennsylvania
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Rhode Island
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South Carolina
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South Dakota
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Tennessee
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Texas
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Utah
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Vermont
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Virginia
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Washington
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West Virginia
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Wisconsin
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Nextech’s intelligent technology platform was built specifically to help med spas deliver outstanding care, maintain compliance, and grow profitability. Request a demo.
Caring for Med Spa Patients on Semaglutide
Patients on semaglutide drugs need careful monitoring and medical management. It’s important providers make the patient aware of the potential risks of rapid weight loss.
When adding semaglutide injections to your med spa’s offers, document standard protocols around use of the drug. Establish clear parameters to determine:
- Which patients are eligible
- How often to administer injections
- Whether and when to adjust the dosage
- How to handle side effects
This documentation not only makes successful outcomes more likely, but can protect you from regulatory and legal liability.
In the initial exam, educate patients about the treatment. Dazzled by success stories they’ve heard from the media and people in their lives, they may not fully understand the potential risks and side effects.
The exam should be performed by a qualified medical professional and should consider more than BMI. You are treating a person, not a condition. Consider their complete health history, including pre-existing conditions, contraindications, lab results, and lifestyle.
No weight loss plan is one-and-done. Your patient will need a long-term plan to stay on track and keep the weight off. Schedule regular follow-up visits to track progress, monitor side effects, and adjust dosage.
An intuitive technology platform like Nextech MedSpa is a valuable tool in these follow-up visits. You can visually track progress at a glance, record a variety of health and lifestyle data points, and get alerted to potential negative outcomes.
Nextech simplifies referrals to nutritionists, dietitians, and other providers who will play an important role in helping your patients adjust to their healthy new lifestyle. You can find referral partners, send pre-filled referral letters with a click, and securely share patient health data with one another.
How to Bill for Semaglutide Treatments
Semaglutide is famously expensive. Out-of-pocket costs are typically in the range of $1,000 a month, and insurance coverage is variable, particularly if weight loss is not treating an urgent medical need.
Before beginning a treatment plan, prequalify the prescription with the patient’s insurer. Tell the patient in advance what their out-of-pocket costs are likely to be, so they don’t start a plan they can’t afford.
To ensure quick and complete reimbursement from insurers, make sure your billing team knows and uses the right codes.
- The ICD-10 code for obesity and overweight is E66, with extensions for morbid obesity, obesity by cause, and obesity by class
- The CPT code for the injection is 96372
Also make sure the exam and risk factor reduction counseling are coded separately from the injection. A practice management system with built-in coding and billing tools takes the load off your staff and helps make sure claims are coded correctly before they go out.
Since insurance coverage for semaglutide varies widely, even patients with insurance may have to pick up a hefty tab. Payment installment plans can make treatment more affordable.
Patients on a manageable payment plan are more likely to make their payments on time, improving your cash flow.
FAQs
Is semaglutide legal for weight loss in my state?
Yes, semaglutide can be prescribed for weight loss anywhere in the U.S. However, some states regulate prescriber supervision, telehealth prescribing, protocols, and scope.
Do med spas need any special licensing to administer semaglutide injections?
No, there is no separate license required for semaglutide. Some states have specific rules pertaining to administration in a non-clinical environment like a med spa, such as collaborative agreements or physician oversight.
What are the rules for compounding semaglutide instead of using the brand-name drugs?
The FDA has not approved any semaglutide formulations outside of the two brand-name drugs on the market.
Compounded semaglutide is only permitted under specific conditions, such as an FDA-declared shortage or if a patient has a documented medical need that the approved formulations cannot meet.
Stay Compliant with an Intelligent Healthcare Platform Specifically Created for Med Spas
Med spas navigate a thorny maze of rules, regulations, and best practices, not just around semaglutide, but around all the treatments they offer.
Nextech developed technology specifically for the unique needs of med spas. This technology helps practices manage shifting regulatory requirements, provide outstanding patient care, and operate a lean, profitable business.
Request a demo today to see what Nextech can offer your practice.
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